Elsevier - Health Sciences Division
Elsevier - Health Sciences Division - Ras Drug Discovery Past Present And Future - Paperback
Elsevier - Health Sciences Division - Ras Drug Discovery Past Present And Future - Paperback
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Binding: Paperback
Description: KRAS Drug Discovery: Past Present and Future is a comprehensive overview of the state - of - the - art medicinal chemistry approaches towards targeting the formerly undruggable oncogene KRAS. It includes Seminal medicinal chemistry case histories of KRASG 12 C inhibitors such as Sotorosib the first approved KRASG 12 C inhibitor for Nsclc alongside the latest advances towards identification of in vivo tools and development candidates targeting KRAS G 12 D KRAS G 13 C and other mutations. The book also provides the reader with a comprehensive overview of the in vitro assay systems in vivo pharmacology xenograft models and chemical biology tools available to characterize small molecule inhibitors of KRAS.
Title: Ras Drug Discovery Past Present And Future
Brand: Elsevier - Health Sciences Division
Barcode: 9780443218613
Pages: 562 Pages
Publication Date: 10/24/2024
Category: Chemistry
Description: KRAS Drug Discovery: Past Present and Future is a comprehensive overview of the state - of - the - art medicinal chemistry approaches towards targeting the formerly undruggable oncogene KRAS. It includes Seminal medicinal chemistry case histories of KRASG 12 C inhibitors such as Sotorosib the first approved KRASG 12 C inhibitor for Nsclc alongside the latest advances towards identification of in vivo tools and development candidates targeting KRAS G 12 D KRAS G 13 C and other mutations. The book also provides the reader with a comprehensive overview of the in vitro assay systems in vivo pharmacology xenograft models and chemical biology tools available to characterize small molecule inhibitors of KRAS.
Title: Ras Drug Discovery Past Present And Future
Brand: Elsevier - Health Sciences Division
Barcode: 9780443218613
Pages: 562 Pages
Publication Date: 10/24/2024
Category: Chemistry
