Hillery Anya Phd (Saint Louis University Madrid Madrid Spain) - Mrna Therapeutics Foundations Innovations And Clinical Applications - Paperback

Binding: Paperback
Description: m RN a Therapeutics: Foundations Innovations and Clinical Applications aims to provide a comprehensive text that covers all aspects of m RN a therapeutics from the foundational science that underpins this disruptive new drug class through the scientific and technological breakthroughs crucial for therapeutic success to the current clinical applications and the innovative advances driving future directions. The book begins with foundational knowledge covering m RN a biology the immune system and vaccines. The second section addresses the major challenges associated with m RN a as a therapeutic modality and the molecular engineering innovations and delivery technologies that have allowed these hurdles to be largely overcome. The third section describes the current and future clinical applications of m RN a therapeutics that are transforming or are poised to transform medicine and health. This includes the use of m RN a vaccines for Covid - 19 and other infectious diseases as well as m RN a's role in revolutionizing cancer immunotherapy covering immunostimulants cancer vaccines including personalized neoantigen vaccines and CAR T cell technologies. Additional chapters describe the use of m RN a therapeutics for protein replacement therapy and gene - editing as well as newer m RN a constructs including self - amplifying m RN a. The final section addresses the safety and regulatory considerations of m RN a therapeutics along with broader cultural issues including vaccine hesitancy global vaccine inequality and pandemic preparedness. Currently m RN a texts either provide personal accounts from key players involved in Covid - 19 vaccine development with limited scientific depth or focus on highly specialized more esoteric applications of m RN a in advanced molecular biology. This book aims to bridge this gap by providing a scientifically rigorous and wide - ranging exploration of m RN a's role in therapeutics. This pioneering textbook serves as a vital addition to the academic canon providing an essential tool for the current and next generation of students scientists researchers and professionals in a wide variety of related disciplines including molecular biology biomedical engineering pharmaceutical science oncology and the health sciences.
Title: Mrna Therapeutics Foundations Innovations And Clinical Applications
Author(s): Hillery Anya Phd (Saint Louis University Madrid Madrid Spain)
Publisher: Elsevier Science Publishing Co Inc
Barcode: 9780443289347
Pages: 210 Pages
Publication Date: 9/12/2024
Category: Pharmacology